Diffusion measurements around lesions have been linked to re-myelination and demyelination, offering a biomarker to measure the effect of new therapies on MS.
- Klistorner, Alexander, et al. “Decoding diffusivity in multiple sclerosis: analysis of optic radiation lesional and non-lesional white matter.” PLoS One 10.3 (2015): e0122114.
- Klistorner, Alexander, et al. “Diffusivity in multiple sclerosis lesions: At the cutting edge?.” NeuroImage: Clinical 12 (2016): 219-226.
Tools: Parametric lesion progression analysis
FDA cleared: Research use