MS Imaging Biomarkers
Accurately determining the location and spread of MS lesions throughout the brain is critical to diagnose and monitor disease progression.
Visual Detection and Categorization of White Matter Lesions
The process of visually detecting, categorizing, and segmenting white matter lesions can be highly time-consuming and inconsistent among readers, yet it's essential in tracking neurological conditions like multiple sclerosis. To aid this process, the QMENTA platform offers a highly configurable viewer with various capabilities such as quality checking, ROI drawing, label editing, annotations, synchronized volumes, and visualization of dynamic sequences. By integrating web viewers with diverse options, the platform not only saves time but also promotes greater standardization, making it an invaluable tool for medical professionals.
Quantitative Susceptibility Mapping (QSM)
A subset of lesions in MS, characterized by a paramagnetic rim from iron-laden microglia, negatively impacts clinical outcomes. Iron-sensitive techniques like gradient echo (GRE) MRI and quantitative susceptibility mapping (QSM) are crucial for detecting and monitoring these lesions.(12)
Changes in Brain Volume as detected by MRI
Patients with multiple sclerosis (MS) experience varying degrees of gray matter atrophy beyond normal aging. The QMENTA platform's tools enable quantification of region-specific atrophy and thickness, utilizing processing tools like FreeSurfer, ANTs, and SIENAX, allowing longitudinal assessment of gray matter atrophy. (5)
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